10 results
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... and anticoagulants ... #coumadin #heparin ... #warfarin #apaxiban ... thrombin #ptt #pt
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... : Rivaroxaban, Apixaban ... K Antagonists: Warfarin ... Inhibitors: Argatroban, Dabigatran ... #Cascade #Anticoagulants
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
on Coagulation ... Tests PT / INR, ... Clotting Time Warfarin ... UFH LMWH Fondaparinux ... Rivaroxaban Apixaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... clotting #INR #heparin ... #LMWH #NOAC #warfarin ... rivaroxaban #Xarelto #apixaban ... #Eliquis #dabigatran
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
- Pathophysiology ... (e.g. warfarin) ... #Heparins #LMWH ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... /LMWH → Protamine ... sulfate - Dabigatran ... (Praxbind) - Apixaban
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
commonly used anti-coagulation ... Molecular Weight Heparin ... (LMWH) - Enoxaparin ... - Warfarin - ... Xa inhibitors - Apixaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Coagulation #Cascade ... thrombin #clot #PT ... anticoagulation #anticoagulant ... #Warfarin #Dabigatran ... thrombin #inhibitor #Apixaban
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early warfarin therapy ... - Rivaroxaban, apixaban ... unfractionated heparin ... - Other anticoagulants ... Supratherapeutic warfarin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor of a coagulation ... integrity Clotting cascade ... Acquired: • Heparin ... , dabigatran, argatroban ... (warfarin, direct