8 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... infection, HBV ... Labs/Diagnosis: ... - GPA, EGPA, microscopic ... Cryoglobulins #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... • ANCA (Dx: GPA ... Low levels mixed cryoglobulinemia ... • HBV HCV
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Palpable purpura • Vesicles ... Differential Diagnosis ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... /HSP • Cryoglobulinemia ... • HCV, HBV Not
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... HTN • Check: HBV ... MPO > PR3 60/ GPA ... / ANCA + MPO) Cryoglobulinemic ... legs), cutaneous vesicles
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Zone Lymphoma (HCV ... Immunotactoid GN & Cryoglobulinemic ... Autoimmunity: • -MM/WM: Vasculitis ... (Cryoglobulinemic ... #Differential #Diagnosis
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
Diagnosis? ... Churg-Strauss syndrome ... #LCV #Hand #skinrash ... #dermatology #clinical ... #photo
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
Diagnosis? ... triad of fever, vesiclar ... Primary papule➡️vesicle ... Eschar #rakari #clinical ... #photo #skinrash