11 results
Comparison - Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Catatonia

- BWH Medicine Chiefs @BrighamChiefs

#Serotonin #Syndrome #Neuroleptic
Comparison - Serotonin ... Malignant Syndrome ... BrighamChiefs #Serotonin ... Catatonia #NMS #SS #comparison ... #diagnosis #management
Signs and Symptoms of Toxidromes

Sympathomimetic / GABAergic withdrawal 
Cholinergic 
Anticholinergic 
Opioid withdrawal 
Neuroleptic malignant syndrome 
Serotonin
Signs and Symptoms ... Neuroleptic malignant syndrome ... Serotonin syndrome ... #Toxidromes #Comparison ... Sympathomimetics #Diagnosis
Serotonin Syndrome
 - Rapid onset 
 - Combination of 2+ serotonin agonists 
Mental status changes:
Serotonin Syndrome ... Combination of 2+ serotonin ... speech Autonomic instability ... #Syndrome #Diagnosis ... #Management
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin ... Syndrome Identify ... normalize vital signs ... illness with VS instability ... #Syndrome #Management
Rapid, increasing signs of extrapyramidal symptoms (EPS) is an important key feature of NMS. EPS, associated
Rapid, increasing signs ... differentiating the two syndromes ... #Diagnosis #Serotonin ... #Syndrome #NMS ... NeurolepticMalignant #Comparison
Neuroleptic Malignant Syndrome - Diagnosis
Neuroleptic Malignant Syndrome is an idiosyncratic reaction to antipsychotic medications classically characterized
- Diagnosis Neuroleptic ... and autonomic instability ... status: • NMS, Serotonin ... status: catatonic signs ... #Diagnosis #neurology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
hyperthermia crisis (late sign ... ) (→ 3-8) • Serotonin ... syndrome (cocaine ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Syndrome: Variable ... make a clinical diagnosis ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... sex • Metabolic syndrome ... forefoot, ankles, knees ... double contour sign ... +Radiographic signs