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diagnosis hematology oncology treatment agglutinin aplastic chronic cll cold cytokine disease genetics hemolytic hemophagocytic hhv8 hlh inflammatory kaposi kics kshv
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Pathogenesis and clinical ... Signs/Symptoms ... • Decr Bone mineral ... pathophysiology #peds
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin color ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Management of Serotonin Syndrome Identify and stop all serotoninergic medications • Avoid inadvertent Rx of serotoninergic meds
Syndrome Identify ... serotoninergic meds ... goal to normalize vital ... signs • Supplemental ... then 2 mg q2h if symptoms
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Infection Clinical ... of anemia include ... • hemolytic anemia ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... • Aplastic Anemia ... Exposure to heavy metal ... • Granulocyte colony ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... • Richter’s Syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
Inflammatory Cytokine Syndrome ... 3, and 4. 1) Clinical ... Symptoms: Fatigue ... abnormalities: Anemia ... Kaposi #diagnosis #management
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