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hematology management msk oncology dermatomyositis hemophagocytic hlh lymphohistiocytosis physicalexam signs symptoms treatment anemia anterior antimda5 antimda5dm antinxp2 antinxp2dm aplastic biceps
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
predispose to other orthopedic ... common sites: hip, shoulder ... Osteomyelitis / Septic ... #differential #diagnosis ... #causes #hematology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Pathogenesis, clinical ... and underlying bone ... #Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... Hemophagocytosis in bone ... • Infection should ... management #treatment #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Management Summary Diagnostic ... Hypercellular bone ... present, symptoms, signs ... aspirin • Aspirin should ... Summary #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Aplastic Anemia Clinical ... Headaches • Pale skin color ... Anemia #oncology #hematology ... #diagnosis #management
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
, and back and shoulders ... (in a shawl sign ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... Warm AIHA • Bone ... workup #oncology #hematology
Yergason's Test on Shoulder Examination Patient Position: Sitting Examiner Position: Standing adjacent to the test arm. One hand
One hand stabilizes ... the shoulder. ... Positive Sign: ... #PhysicalExam #clinical ... #video #msk #orthopedics
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 Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Exposure to heavy metal ... • Granulocyte colony ... blood smear • Bone ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... auricular papules Clinical ... renal carcinoma • Colon ... #management #rheumatology ... #dermatology
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