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hematology management oncology dermatomyositis disease hemophagocytic hlh lymphohistiocytosis anemia antimda5 antimda5dm antinxp2 antinxp2dm aplastic arthritis behcet bone causes chronic cll
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
predispose to other orthopedic ... common sites: hip, shoulder ... Osteomyelitis / Septic ... #differential #diagnosis ... #causes #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... present, symptoms, signs ... aspirin • Aspirin should ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... • Bicytopenia Treatment ... • Infection should ... #hematology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
hands/feet, knees, shoulders ... Signs & Symptoms ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... #management #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
, and back and shoulders ... (in a shawl sign ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... erythema nodosum (septal ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... workup #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin color ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Exposure to heavy metal ... • Granulocyte colony ... factor (GCSF) treatments ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... auricular papules Clinical ... renal carcinoma • Colon ... #management #rheumatology ... #dermatology
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