1985 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... Pathophysiology #Allergy
Angioedema: Acute swelling of the lips resulting from an allergic response to medication

Charlie Goldberg, M.D. -
resulting from an allergic ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Allergy
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... antigens, leading to complement ... they activate complement ... reactions #types #allergy
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... infections • Clinical ... is rare Normal complement ... response: The complement ... cell membranes -> Critical
Allergic Rhinitis
Mild to severe persistent nasal mucosal inflammation to specific allergic triggers
WHO? 
 • 1 in
Allergic Rhinitis ... inflammation to specific allergic ... Sinusitis • Allergic ... Conjunctivitis Clinical ... NUIM_Chiefs #Allergic
Algorithm for Suspected Penicillin Allergy in Patients Undergoing Surgery 

• Cephalosporins may be prescribed to patients
Suspected Penicillin Allergy ... reported penicillin allergy ... physicians use the clinical ... true penicillin allergy ... #Penicillin #Allergy
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... dead tissue • Complement ... activation of complement
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Penicillin Allergy ... With Penicillin Allergy ... HSR), EMR lists allergy ... there is a strong clinical ... #Penicillin #Allergy