8 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... #TypeI #Type1 #HypersensitivityReaction ... #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
TypeIII #Type3 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
activates the complement ... #Type2 #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... Classification #Pathophysiology ... #Allergy #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm
INDICATIONS FOR TESTING:
 • Recurrent angioedema (without urticaria)
 •
Complement 1 esterase ... Deficiency Testing Algorithm ... ARUPLabs #C1INH #Complement ... Deficiency #Testing #Algorithm ... #allergy #diagnosis
Amebiasis - Balamuthia mandrillaris Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans
who are immune competent ... #mandrillaris #LifeCycle ... #diagnosis #pathophysiology