28 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Types: • Type ... • Low serum C4 complement ... #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... , seasonal hay fever ... antigen, leading to complement ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... antigens, leading to complement ... they activate complement ... allergy #table #classification
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Coronary arteries - Fever ... : • Fevers • ... against MPO • Complement ... #rheumatology #classification
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... ; however, an algorithmic ... petechiae/purpura with fever ... require emergent evaluation ... petechiae/purpura with fever
Chest Pain / ACS Evaluation Algorithm
Algorithm that attempts to the use history taking (guided by LRs),
Chest Pain / ACS Evaluation ... Algorithm Algorithm ... Diamond-Forrester classification ... physical activity - Nausea ... ChestPain #ACS #Evaluation
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
pyelonephritis Most common cause ... uncharacterized fevers ... Consider BCx, CSF evaluation ... Diagnosis #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Infection - Vasculitis ... Red Flags: • Fever ... #Causes #dermatology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss Types ... the most common type ... The evaluation should ... • Stroke • Vasculitis ... cause unknown)