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diagnosis allergy rheumatology immunology differential cryoglobulinemia cryoglobulins glomerulonephritis hypersensitivity igg4 large management medium progressive rapidly reactions rpgn small table type1
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... antigen-antibody complexes ... sickness #TypeIII #Type3 ... #HypersensitivityReaction ... Allergy #Immunology #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... antigen-surface complex ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... Allergy #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... allergen-antibody complex ... Allergen-antibody complexes ... #Type1 #HypersensitivityReaction ... Allergy #Immunology #pathophysiology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... by large vessel vasculitis ... although immune complex ... can affect any type ... Medium #Large #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... Types: • Type ... • Type III Often ... • Vasculitis ... #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... Their Mechanisms Type ... Antigen-antibody complexes ... #Classification ... #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... immunofluorescence Immune Complex ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... • Pancreas: Type ... aortitis, mimics vasculitis ... complement • Classification
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