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diagnosis infections differential betadglucan brain causes galactomannan management aids aspergillus bacteremia biomarkers coccidioidomycosis comparison evaluation falsepositives febrile hiv laboratory mycoses
ID Approach to Fever and Rash - Diagnostic Algorithm Central Maculopapular (most common): Measles, Parvovirus 819 / EBV,
ID Approach to Fever ... Rash - Diagnostic Algorithm ... Disseminated fungal ... Febrile #Diagnosis #Algorithm ... #Schema #InfectiousDiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... decreased with: concurrent ... Clav (may be + as long ... post-2010 almost never
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... #Infections #Concurrent ... Diagnosis #causes #infectiousdiseases
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... #Infections #Concurrent ... Diagnosis #causes #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... cough, myalgia • Lung ... Microsporidium #Lung ... differential #diagnosis #infectiousdiseases
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
hypothalamus → fever ... Lipopolysaccharide components ... Double-stranded RNA • Fungi ... Mannan and glucan components ... Pathophysiology #InfectiousDiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... Sensitivity ↓ w/concurrent ... result in + as long ... post-2010 almost never
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... change in the lungs ... • Isolated fever ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Key Components: ... or family - Ever ... physical exam - Key components ... event, follow ACC algorithm ... unless prior heart/lung
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
Coccidioidomycosis (Valley Fever ... known as valley fever ... , is a fungal infection ... spherules in the lungs ... Diagnosis #Management #infectiousdiseases
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