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diagnosis management betadglucan galactomannan infections invasive latenttb tb tuberculosis bacteremia biomarkers comparison falsepositives fever ia infectousdiseases laboratory mycoses pyrogen rigors
Invasive fungal infections: Morphology, Risk Factors, Disease Characteristics, Diagnostic Tools, First-Line Treatment Aspergillus, Mucorales, P. Jiroveci, Cryptococcus,
Invasive fungal ... Tools, First-Line Treatment ... Aspergillus, Mucorales ... #Invasive #Fungal ... #Infections #InfectousDiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... of many fungi ... admin of mold-active ... Sara Dong #Fungal
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Double-stranded RNA • Fungi ... Mannan and glucan components ... vasculature via: • Active ... #InfectiousDiseases
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Invasive Aspergillus ... and Management Aspergillus ... this morphology Treatment ... Diagnosis #Management #treatment ... #fungal #infectiousdiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... concurrent admin mold-active ... closely related fungi ... Galactomannan #Fungal
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
Fever - Pyrogen Pathophysiology ... Lipopolysaccharide components ... stranded RNA • Fungi ... Mannan and glucan components ... vasculature via: • Active
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... infection (NTM) • Fungal ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Diagnosis: • Direct fungal ... ASPERGILLOSIS • Aspergillus ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... infection (NTM) • Fungal ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
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