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diagnosis differential rheumatology dermatology generalized pruritus secondary symptoms vasculitis addisons classification insufficiency management scleroderma sclerosis sjogrens ssc syndrome testing vasculitides
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Primary Causes ... == Primary Skin ... Skin Lesion / Systemic ... BUN: • Chronic renal ... #causes
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening Signs ... Hepatic: PBC (primary ... : scleroderma renal ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
CLINICAL MANIFESTATIONS OF ADRENAL INSUFFICIENCY. Primary and secondary adrenal insufficiency: - Tiredness, weakness, mental depression
Primary and secondary ... hypotension - Nausea ... Central nervous system ... disorders: - Pale skin ... Insufficiency #Signs
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... BUN: • Chronic renal ... Pruritus #secondary #systemic ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary ... tract, and often causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Vaginal dryness • Primary ... ab (specific in primary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic
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