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diagnosis differential management dermatology generalized pruritus secondary symptoms vasculitis workup arteritis autoimmune classification cryofibrinogenemia disorders eosinophil eosinophilia gca giantcell hemeonc
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... thickening Signs ... Hepatic: PBC (primary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Primary Causes ... == Primary Skin ... Skin Lesion / Systemic ... #causes
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... processes: • Systemic ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... up EPO levels Primary ... #workup #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... central nervous system ... Presentation - Systemic ... purpura: strong sign ... differential #diagnosis #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
sx + signs/sx of ... required due to skip ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... GCA #Temporal #Signs
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... Pruritus #secondary #systemic ... #causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Vaginal dryness • Primary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
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