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diagnosis betadglucan fungal galactomannan management perioperative active anesthesia anesthesiology aspergillus biomarkers causes comparison differential evaluation falsepositives hyperthermia infectiousdiseases laboratory latent
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Tuberculosis Testing ... result with no clinical ... • History of BCG ... immunocompromised (e.g ... #Diagnosis #Workup
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... production • Actively ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... malignant syndrome (e.g
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Clinical Manifestations ... on EMG - Absence ... of diazepam • EMG ... antibody that works ... TPO, TTG, etc EMG
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Key Components: ... event, follow ACC algorithm ... indicated • EKG ... Obtain EKG if: ... Change in clinical
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Polysaccharide cell wall component ... cut-offs defined in clinical ... formulations (e.g ... beta-glucans (e.g ... admin of mold-active
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... • Cell wall component ... formulations (eg ... >90% (In most clinical ... concurrent admin mold-active
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