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diagnosis betadglucan galactomannan perioperative anesthesia anesthesiology aspergillus biomarkers causes comparison differential evaluation falsepositives hyperthermia laboratory management preop preoperative risk sensitivity
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Polysaccharide cell wall component ... cut-offs defined in clinical ... formulations (e.g ... beta-glucans (e.g ... Frozen ice-pops (in setting
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... malignant syndrome (e.g ... Diagnosis #Management #Workup
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Key Components: ... event, follow ACC algorithm ... indicated • EKG ... Obtain EKG if: ... Change in clinical
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... • Cell wall component ... cut-offs defined in clinical ... formulations (eg ... >90% (In most clinical
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