21 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphadenopathy, Confusion ... : ↑↑ ferritin, Anemia ... IL-2 receptor Diagnostic ... Criteria): Molecular diagnosis ... #hematology #criteria
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... Hypothyroid • Liver ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... Renal Disease, Liver ... #Algorithm #Causes ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5. ... Acquired Aplastic Anemia ... #Algorithm #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... Non-megaloblastic: Liver ... #MCV #Algorithm ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... HLH syndrome 5 ... Acquired Aplastic Anemia ... #Algorithm #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Algorithm Normal ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Algorithm Decreased ... Megakaryopoiesis • Aplastic Anemia ... Alloimmune • anti-HLA ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Presentation / Diagnosis ... Diagnosis via genetic ... lymph node, or liver ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
with leukopenia, anemia ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology