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Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Syndrome Testing Algorithm ... dexamethasone suppression test ... Urine Free by LC-MS ... /MS) • Adrenocorticotropic ... Syndrome #diagnosis #algorithm
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test T-1m: Baseline cortisol drawn T0: 250 µg cosyntropin given IV T30m: Repeat
Insufficiency Algorithm ... Cosyntropin Stimulation Test ... T-1m: Baseline cortisol ... IV T30m: Repeat cortisol ... Insufficiency #Testing #Algorithm
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... clue • Blood tests ... ACTH stimulation test ... present - ACTH test
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis Algorithm ... unclear (often the case ... Standard Stim test ... Insufficiency #Diagnosis #Algorithm ... #Stimulation #Test
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
ACTH stimulation test ... not stimulate cortisol ... ACTH • Serum cortisol ... aldosterone - Low in cases ... - Serum tests that
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... Step 1) Screening Test ... ) Confirmation Test ... This test determines ... Insufficiency #Algorithm
Chronic Shoulder Pain - Differential Diagnosis Algorithm 4 tests for the AC joint: 1. Direct palpation 2. Cross-arm shoulder
Differential Diagnosis Algorithm ... 4 tests for the ... after cross-arm test ... Differential #Diagnosis #Algorithm ... #MSK
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Renal ultrasound, Tests ... sodium loading test ... saline infusion test ... h urinary free cortisol ... midnight salivary cortisol
Adrenal Insufficiency Diagnosis Algorithm Clinical features: - Weight loss, anorexia, Weakness, fatigue, GI distress - Hypotension,
Insufficiency Diagnosis Algorithm ... : - AM serum cortisol ... unlikely - If serum cortisol ... cosyntropin stimulation test ... interact with stim test
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
: Most Common Cause ... Adrenalitis Other causes ... Causes of Secondary ... A STIM test can ... ACTH STIM TEST:
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