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differential algorithm anemia causes disease disorders hemolytic oncology arthritis cold eosinophil eosinophilia hodgkins laboratory lymphoma management mds myelodysplasia myelodysplastic petechiae
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... Immunoglobulin M (IgM) • Blood ... post infectious setting ... sensitize red blood ... hemolytic #anemia #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... evaluation or workup ... 1,500 cells/µL Workup ... #Differential #diagnosis ... #hematology #eosinophilia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Agglutination - Cold agglutinins ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... plateletcount), peripheral blood ... smear, HIV/HCV testing ... (CVID, WAS), (neurologic ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... deficiency Work ... : • Complete blood ... test • Serology ... Algorithm #Causes #dermatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Polyarthritis: • Blood ... : • Complete blood ... (to support a diagnosis ... #diagnosis #testing
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... : • Full Blood ... marrow biopsy - if blood ... #classification ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... Treatment: Goals: Treating ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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