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management infections opportunistic pharmacology prevention cytomegalovirus diagnosis hemophagocytic hhv8 hlh kaposisarcoma lymphohistiocytosis rheumatology summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... +: Virus (EBV, CMV ... Histoplasmosis, candidiasis ... or biologics (CMV
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
IDSA Recommendations ... , Multicentric Castleman ... • Since low CD4 ... #IDSA #Prevention ... opportunistic #infections #HIVAIDS
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
IDSA Recommendations ... ART to maintain CD4 ... effective for treatment ... #IDSA #Prevention ... opportunistic #infections #HIVAIDS
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