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diagnosis differential causes infections infectiousdiseases cardiology fungal management aspergillus betadglucan biomarkers cns comparison galactomannan lesions mycoses neurology radiology ringenhancing
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... phenomena from endocarditis ... Mucormycosis, Cryptococcus ... #Lung #Infections
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... phenomena from endocarditis ... Mucormycosis, Cryptococcus ... #Lung #Infections
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... phenomena from endocarditis ... Mucormycosis, Cryptococcus ... #Lung #Infections
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lesions • 80% with lung ... histoplasmosis, cryptococcus ... RingEnhancing #Lesions #Brain
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... decreased with: concurrent ... Clav (may be + as long
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Endocarditis Summary ... verrucous) • Lung ... Prosthetic Valve Endocarditis ... Aspergillus • Cryptococcus ... #Endocarditis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fluconazole CRYPTOCOCCUS ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... • Sinusitis • Brain ... arthritis, and endocarditis
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... , verrucous) - Lung ... Prosthetic Valve Endocarditis ... Aspergillus • Cryptococcus ... #Endocarditis
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