9 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease ... Pruritus #primary #secondary ... #dermatology #Differential
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Vascular reactivity (Skin ... processes: • Systemic ... Antiphospholipid syndrome ... Warfarin-induced skin ... #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Purpura - Skin ... • Autoimmune diseases ... Type III Often Secondary ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis #rheumatology ... #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Disease Classification ... in the context ... Seizures • Strokes Skin
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... its creatinine content ... central nervous system ... nose (epistaxis), skin ... loss, causing secondary
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... • Secondary form ... Central nervous system ... amyloidosis, PAH Skin ... Nephrogenic DI Hematologic
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
• Presence of systemic ... membrane bleeding and skin ... Marfan syndrome, ... History #peds #pediatrics ... #diagnosis #hematology