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diagnosis differential management rheumatology agglutinin als amyotrophic anemia behcet cancer cold cryofibrinogenemia emergencies hemolytic lateral manifestations monoclonal myelitis neurological oncologic
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... of Cold Sensitive ... Cold Agglutinins ... sensitize red blood cells ... hemolytic #anemia #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... neutrophil count < 500 cells ... Epidural Spinal Cord
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... lesion Pott's Disease ... lymphadenopathy, pulmonary ... Children with pulmonary
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... Cryofibrinogenemia Symptoms ... may include: • Cold ... #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... to the spinal cord ... at the spinal cord ... Bilateral signs and/or symptoms ... diagnosis #management #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... matter, spinal cord ... meningitis), MCC CNS symptoms ... management #signs #symptoms ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... anemia due to cold ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Multinucleated giant cells ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... multiple spinal cord ... course of the disease ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
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