14 results
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... - Differential Diagnosis ... Clearance: Systemic liver ... sugars in the colon ... #Acidosis #Differential
Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Differential diagnosis ... central dot. - LIP ... #Clinical #Diagnosis ... #Radiology #CTChest ... #Differential #Comparison
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Metformin Associated Lactic ... cycle found in the liver ... kidney injury are common ... presentation - Clinical ... #Management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... Diagnosis The ... most common causes ... Ethylene glycol - HIV ... #Differential #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... underarms, or chest ... the spleen or liver ... #oncology #diagnosis ... #differential #
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
Aka pyroglutamic acidosis ... paracetamol use common ... deficiency) • Liver ... undetectable • Lactic ... #management #treatment
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
hepatitis and lactic ... acidosis, and Aortic ... restored to esophagus Clinical ... formation is the most common ... #management #gastroenterology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
and Clinical Manifestations ... pulmonary HTN is common ... also seen • Lactic ... acidosis may not ... GFR • Acute liver
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... Ketoacidosis (AK) we commonly ... But we also have Lactic ... #diagnosis #differential ... #algorithm #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... Chest CT: • Ground-glass ... and M panel Management ... #management