9 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Oral #Anticoagulant ... #Anticoagulation ... #Rivaroxaban #Edoxaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) - Heparin ... /LMWH → Protamine ... sulfate - Dabigatran ... #doac #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents ... 80% Renal Edoxaban ... 35% Renal #DOAC ... #NOAC #Metabolism ... #anticoagulation
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
accelerates the bridging ... : A new oral anticoagulant ... #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... clotting #INR #heparin ... #LMWH #NOAC #warfarin ... #coumadin #rivaroxaban
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
and rivaroxaban ... filtration rate; DOAC ... weight heparin; ... #DOAC #VTE #Malignancy ... #Anticoagulation
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... Anticoagulants ... and edoxaban. ... thrombin time #doac ... #noac #anticoagulation
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
**Edoxaban is initiated ... DOAC, direct oral ... heparin. ... #DOAC #VTE #Malignancy ... #Anticoagulation
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... determine timing of DOAC ... ) • Apixaban, Edoxaban ... , Rivaroxaban (anti-XA ... postoperative #DOAC