11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #INR #heparin #LMWH ... #coumadin #rivaroxaban ... #Pradaxa #management
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... (e.g. heparin, LMWH ... warfarin) for chronic anticoagulation ... accelerates the bridging ... #UFH #DOAC #Dabigatran
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... Edoxaban (Lixiana), Rivaroxaban ... PCC (Kcentra) #anticoagulation
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Management Cheat ... Warfarin, Apixaban, Dabigatran ... , Rivaroxaban ... #Anticoagulant ... #DOAC #Management
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Weight Heparin (LMWH ... #anticoagulation ... #medications #doac ... #comparison #table ... #management #drugs
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from LMWH ... Switching from DOAC ... #Bridging #anticoagulation ... #pharmacology #management
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
, edoxaban and rivaroxaban ... direct-acting oral anticoagulants ... ; LMWH = low molecular ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... patients on chronic anticoagulation ... to assess for anticoagulant ... of Therapy • Dabigatran ... Apixaban, Edoxaban, Rivaroxaban
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
typically needed • DOACs ... thrombin inhibitor (dabigatran ... Xa inhibitors (rivaroxaban ... #diagnosis #management ... #cardiology