7 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Alcohol, Viral hepatitis ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... Production: • Albumin ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Diagnosis High ... - Alcoholic hepatitis ... Veno-occlusive disease - Acute ... fatty liver of ... #Diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Hepatitis, Preeclampsia ... #Pregnancy #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... INR, bilirubin, albumin ... • Cirrhosis/acute ... hepatitis • Infiltrative ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Total Protein - Albumin ... concentration minus albumin ... Sarcoidosis) • Liver ... Gap #ProteinGap #differential ... #diagnosis #hematology