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differential algorithm lfts obstetrics pregnancy biliary causes chemistry cholangitis cirrhosis comparison disease fatty hellp icp injury interpretation liverenzymes management obgyn
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Hepatitis, Preeclampsia ... Pregnancy #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... #differential # ... diagnosis #algorithm ... #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
obstruction • ALP ... or higher • Liver ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
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