26 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Bleeding disorders in children

#Bleeding #Disorders #Differential #Hematology #Pediatrics #Peds
Bleeding disorders ... in children #Bleeding ... #Differential #Hematology ... #Pediatrics #Peds
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... distinctive primary granules ... • Significant bleeding ... #Leukemia #Hematology
Seborrheic keratosis 
 - Well-circumscribed, stuck-on appearance 
 - Waxy texture 
 - Verrucous surface
have crumbly, granular ... rapid growth, or bleeding ... Seborrheic #Keratosis #Dermatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... neurology, back pain Haematology ... cell disease Rheumatology ... Pathway #Child #Peds
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... Treatment - Acute Bleeding ... Avoid meds that ... ↑ bleeding risk ... Management #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... not required in all ... or if a primary hematologic ... Causes #Workup #hematology
Esophageal Variceal Bleeding - Scoping Summary
GENERAL PRINCIPLES OF MANAGEMENT (VARICEAL-B):
V - Vasoconstrictor therapy: (Octreotide 50mcg bolus
Esophageal Variceal Bleeding ... acquired/vasoactive meds ... outcomes Hayat et. al ... presentation AL ... - Refractory Bleeding
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(Alk phos/ULN ALP ... • AST/ALT > ALP ... disease • If ALP ... RBC (hemolysis, bleeding ... #differential #Hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... Malignancies (eg CML, ALL ... #differential #hematology