10 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... without platelet ... MYH9-Related Disorder ... α-granules (contains ... differential #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... aggregation to all ... count and platelet ... • Platelet flow ... #disorders #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet ... Disorders - Differential ... not required in all ... or if a primary hematologic ... Causes #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... Thrombocytopenia • Platelet ... NON-PALPABLE PURPURA: Platelet ... - PNH - APLS ... Differential #Diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Rash: - ITP - APLS ... Algorithm #Causes #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... to a low blood platelet ... neutrophils and platelets ... Disorders • Nutritional ... Syndromes #diagnosis #hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... a decrease in all ... 13 g/dL in men, platelets ... that involves disorders
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Evaluating Bleeding Disorders ... relatives (if all ... characteristic of platelet ... #History #peds ... pediatrics #diagnosis #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
abnormality is platelet ... widely varying platelet ... hemoproliferative disorder ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... - Low Hb and platelets ... classification #hematology