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diagnosis hematology management oncology differential leukemia algorithm classification cll common cvid hodgkins hypogammaglobulinemia hypokalemia hyponatremia immunodeficiency immunology lymphoma mds myelodysplasia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Neutropenia, anemia ... microglobulin Treatment ... • Richter’s Syndrome ... #diagnosis #workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... skin that are caused ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... - Diuretics (carbonic ... megaloblastic anemia ... differential #diagnosis #nephrology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia is usually caused ... 3 questions to work ... correction of chronic ... demyelination syndrome ... #management #nephrology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... antibody that works ... Treatment: • ... #neurology
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