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signs sle erythematosus pathophysiology systemic differential giantcell rheumatology temporal vasculitis autoantibodies classification gastrointestinal gca management mimickers msk mucocutaneous musculoskeletal neurology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... - Arthralgia, Arthritis ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Gastrointestinal Manifestations ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Signs/Symptoms ... superimposed by waves ... #Signs #Symptoms ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... : - Arthritis ... Differential Diagnosis ... autoantibodies #signs ... #symptoms #mimickers
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... Mucocutaneous #Manifestations ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... pain • Extra-CNS complications ... disorders (Systemic lupus ... #diagnosis #neurology ... #symptoms #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
and ophthalmic complications ... those coming off aorta ... Manifestations depend ... systemic sx + signs ... #Symptoms #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... branches • GCA: - Aorta ... such as systemic lupus ... Presentation - Systemic Symptoms ... purpura: strong sign
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