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differential rheumatology signs management arthritis cardiology ecg electrocardiogram equivalents joint pathophysiology rheumatoidarthritis stemi vasculitis approach autoimmune classification emergency extraarticular gca
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... of Joint Disease ... (RA) and many other ... #MSK #rheumatology ... #differential #diagnosis
STEMI Equivalents on ECG • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
segment at (or 40-60 ms ... J point • De Winter ... V2 • Wellens sign ... • Wellens sign ... #EKG #diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... (RA): Extra-articular ... interstitial lung disease ... pathophysiology #signs ... #symptoms #diagnosis
Approach to ECGs - Ischemia MI = Biomarkers + ECG or echo/angiogram findings Pathologic Q - 1/3 height
Equivalents / Don't Miss Signs ... bigger than QRS - deWinter ... -4 can have no pain ... triple vessel disease ... #EKG #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Diagnosis Framework ... noninflammatory Signs ... constitutional symptoms ... Symmetrical: • RA ... #Diagnosis #MSK
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... and Joint diseases ... poly-articular joint pain ... arthralgia (joint pain ... #symptoms #diagnosis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Sensitivity to pain ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... lesions) McDonald diagnostic
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... claudication: pain ... chews, not just pain ... #Symptoms #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... < 30 years - Aorta ... branches • GCA: - Aorta ... Presentation - Systemic Symptoms ... purpura: strong sign
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... < 30 years • Aorta ... ): • Aorta and ... tract: Abdominal pain ... • Progressive symptoms
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