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diagnosis algorithm causes rheumatology systemic hemolytic management symptoms generalized hemolysis hemophagocytic hlh lymphohistiocytosis oncology pruritus vasculitis abnormal agglutinin aids alopecia
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm Signs ... : Membrane defects ... #Differential # ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology ... #secondary
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... : Sickle cell anemia ... #Hemolysis #Differential ... #Diagnosis #hematology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... Wernicke-Korsakoff syndrome ... , neural tube defects ... Vitamins #Deficiency #differential ... #diagnosis #signs
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... • Nephrotic syndrome ... NailDisorders #Systemic #Secondary ... #dermatology #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
the Nikolsky sign ... , the differential ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Febrile #Fever #Differential
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
- Generalized Differential ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
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