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diagnosis hematology hemolytic causes algorithm cold disease extravascular hemolysis hospitalization pathophysiology pseudoanemia testing thromboticthrombocytopenicpurpura ttp
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
. primary cold agglutin ... Intrinsic RBC Defects ... #Causes #differential ... #diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... younger pts) Differential ... the RBCs causing intravascular ... : High fevers, chills ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold agglutinins ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
low, tests to detect ... reflection of intravascular ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
invasive procedures/ bleeding ... bedrest’s negative effects ... phlebotomy/ blood work ... other than GI bleeding ... pathophysiology #differential
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