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diagnosis management differential neurology hematology rheumatology bee chagas chronic coronavirus covid19 disease hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis multiple multisystem myelitis
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... Clinical features all ... coronavirus #diagnosis #Signs ... #Symptoms
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
nervous system • Inflammatory ... • Or brainstem syndromes ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... • Richter’s Syndrome
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory ... diagnosis and treatment ... Non-inflammatory ... nasal squamous cell ... consistent with MS
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... Diagnosis: HLH signs ... and symptoms can ... Low or absent NK cell
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... preferentially affects ... • Bilateral signs ... and/or symptoms ... Transverse Myelitis Treatment
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Chagoma: inflammatory ... Romana's sign ... Indeterminate form (No signs ... /symptoms, positive ... IFA) assays to detect
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... claudication, pulse deficits ... • Progressive symptoms ... : Ocular inflammatory
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
all ethnicities ... Symptoms: • ... + Nonspecific symptoms ... chondritis • Inflammatory ... affected tissue Treatment
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