26 results
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
) An rare systemic ... Affects children ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Restrictive lung defect ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
• Arthropod bites ... Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #diagnosis #differential
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(AQP4-lgG disease ... Motor and sensory deficits ... autoimmune disorders (Systemic ... diagnosis #neurology #symptoms ... #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... papilledema • Horner syndrome ... • Neurological deficits ... pupil (AACG) • Systemic ... symptoms and signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... #Diagnosis #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... and Symptoms: ... development of skin symptoms ... , breast CA - Hematologic