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diagnosis differential hematology management leukemia oncology treatment vasculitis autoimmune bone bony chagas classification hemophagocytic hlh knee lesions lymphocytic lymphohistiocytosis msk
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... ) CLL Symptoms: ... response to mosquito bites ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease
Diagram of different types of bone tumors that can occur around the knee on XRay Age <
Healed NOF • Giant cell ... tumor • Chronic ... phase • Paget disease ... blade of grass sign ... #XRay #MSK #pediatrics
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Romana's sign ... Indeterminate form (No signs ... /symptoms, positive ... IFA) assays to detect ... 90-120 days • Pediatric
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
most frequently affects ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... Low or absent NK cell
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... claudication, pulse deficits ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... Differential #Diagnosis #Rheumatology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
• Associated symptoms ... evaluation for giant cell ... and long head biceps ... treatment for PMR is a chronic ... Diagnosis #Management #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... vasculitis) - Affects ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... caused by toxic effects ... muscular atrophy • Chronic
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