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diagnosis differential management hematology treatment algorithm autoimmune chronic gravis headache hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis mnemonic ms multiple myasthenia myopathy
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... SIGNS/SYMPTOMS ... Signs and symptoms
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... • Neurological deficits ... • Meningeal signs ... ) • Systemic symptoms ... and signs (e.g.
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Paraneoplastic effects ... - Myotonic dystrophy ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... Diagnosis: HLH signs ... and symptoms can ... Low or absent NK cell
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... the skin, neurologic ... • Progressive symptoms ... deficits, TIA and ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... elevated < PM and DM ... caused by toxic effects
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