17 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
• Brushfield spots ... iris (pigmented spots ... Congenital heart defects ... #PhysicalExam #Features ... #Signs #Manifestations
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Features of a Sickle ... Sickle-cell disease ... Sickle cell disease ... The underlying pathophysiology ... #Signs #Symptoms
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Diagnosis and Management ... Summary A defect ... intrinsic lung disease ... HPS Diagnostic Criteria ... resolution of HPS features
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... #Disease #Tuberculosis
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... other suggestive features ... effusion, or z scores ... clinical and lab signs ... Pediatrics #Kawasaki #Disease
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... and with limb features ... course of the disease ... neurology #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Afferent pupillary defect ... McDonald diagnostic criteria ... taper 3-7 days - Short ... sclerosis #diagnosis #management
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... features • RA ... affects 1% of population ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... arrhythmias, congenital defects ... -> Cherry-red spot ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Most commonly affects ... the knee hip and ... > Stiffness is short-lived ... JointPain #Diagnosis #pathophysiology