13 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... taper 3-7 days - Short ... sclerosis #diagnosis #management
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
thrombosis of short ... field: altitudinal defect ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... sex • Metabolic syndrome ... forefoot, ankles, knees ... double contour sign ... +Radiographic signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
arrhythmias, congenital defects ... anti-coagulation • Hematologic ... -> Cherry-red spot ... #ophthalmology ... #diagnosis #signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
must be ruled out ... damage & blindness Signs ... • Visual field defects ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Commonly affects ... grow slowly out ... the nail grows out ... seen in Reiter's syndrome ... Diagnosis #Clinical #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... claudication, pulse deficits ... purpura, joint & gut ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome