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A System for Vasculitides 

#Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... Small #Medium #Large ... #Vessel #Size #Classification ... #Differential #Algorithm
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
involvement by large ... Large vessel vasculitis ... affects large arteries ... can affect any type ... #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Types: • Type ... • Cryocrit - Detect ... disorder (e.g. systemic ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
) - Affects the ... , arthritis LARGE ... central nervous system ... Vessel Size: • Large ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... ANCA-associated vasculitis ... Kikuchi disease • Type-I ... the small and large
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
IV RTA, TYPE I ... ) • Cutaneous vasculitis ... Vasculitis: • ... cell lymphoma • Large ... Rheumatology #Diagnosis #Management
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM

What Are Demyelinating Diseases?
• Conditions that damage myelin, the protective
CENTRAL NERVOUS SYSTEM ... central nervous system ... • Clinical Types ... - Symptom management ... • Imaging: Large
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... smallpox-diagnostic-algorithm-poster ... The type of specimen ... See table below
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
virtually any organ system ... Langerhans cells, a type ... • Affects both ... Immunophenotyping: • Large ... Histiocytosis #Diagnosis #Management