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hematology chronic cll leukemia lymphocytic anemia anthracycline aplastic cardiology cardiotoxicity checkpointinhibitor classification hemeonc hemophagocytic her2 hlh hodgkins lymphohistiocytosis mds myelodysplasia
Immune Checkpoint Inhibitor Toxicity Main Toxicities: Colitis, Pneumonitis, Skin adverse events, Endocrine dysfunction, Hepatitis, Myocarditis,
Incidence, Symptoms ... Complications and Treatment ... SideEffects #Table #Diagnosis ... #Pharmacology # ... Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
to large cell lymphoma ... benefit of immediate chemotherapy ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... , B-cell lymphoma ... Anti-infectious, chemotherapy ... #management #treatment ... #summary #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Erythema nodosum • Immune ... ingestion • B symptoms ... Treatment • Early ... #hematology #oncology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... microglobulin Treatment ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Cytotoxic drugs/Chemotherapy ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Significance (IDUS) • Immune ... ) • Intensive chemotherapy ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... heart failure symptoms ... ) and initiate treatment ... #pharmacology # ... toxicity #chemotherapy
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