Dementia Score causes dermatology secondary anemia diagnosis primary insufficiency management purpura coagulation hemolytic common

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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... intravascular coagulation ... thrombocytopenic purpura ... usually IgM) (e.g. primary ... #hematology #anemia

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

Diagnosis Framework ... /Quantity: • Primary ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #nonpalpable #dermatology

Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell

infection risk secondary ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... #diagnosis #management

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