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diagnosis dermatology differential management rheumatology generalized pruritus secondary acute cryofibrinogenemia dili dress druginduced hepatology injury liver retroviral sjogrens stages syphilis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Primary Causes ... == Primary Skin ... Skin Lesion / Systemic ... Myelodisplastic syndrome ... #causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... toxic aetiology: Skin ... non-essential drug/HDS treatments ... for alternative causes ... #hepatology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
• Symptoms of primary ... sweats (28%) • Skin ... Central nervous system ... -1 p24 core Ag - ... antibody test) Treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... TYPE IV RTA, TYPE ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #causes
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Edema in 70% of cases ... Skin involvement ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
responsible for most cases ... malaise, anorexia, sore ... weight loss • Skin ... Albuminuria, nephrotic syndrome ... individuals with HIV
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
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