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rheumatology activation adult algorithm aosd classification dermatology dress hemophagocytic hlh hodgkins incomplete kawasaki leukemia lymphohistiocytosis lymphoma macrophage mas onset pediatrics
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... Infants ≤6 months ... old on day ≥7 of fever ... within 10 d of fever ... #Diagnosis #Peds
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... - Yamaguchi criteria ... a sore throat, ... #rheumatology # ... management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... Fever >38.5 2. ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... frequently affects infants ... age, however the disease ... following: • Fever ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Periodic fever ... - Nonremitting fever ... Histopathologic criteria ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... activity • ↓ LAP Score ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... number of sites of disease ... through Ann Arbor criteria ... classification #hematology ... #oncology #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... and fatigue Criteria ... Sarcoidosis • Behcet disease ... /EGPA • RA Diagnosis ... #diagnosis #management
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