16 results
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors and Inotropes ... Increase SVR > Inotropy ... #criticalcare # ... pharmacology #comparison ... #shock #management
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
- Pharmacology ... • Higher doses cause ... cAMP/cGMP • Causes ... #Pharmacology # ... Summary #management
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors and Inotropes ... #Vasopressors #Inotropes ... #management #criticalcare ... comparison #table #pharmacology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... Bradyarrhythmias, Some cases ... #Vasopressors #Inotropes ... comparison #table #pharmacology ... #criticalcare
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... in blood flow caused ... Depends on the cause ... #Comparison #criticalcare
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... force (negative inotropy ... Vaughan #Williams #Pharmacology ... #Classification ... #Classes #pathophysiology
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
hospitalization) • Pathophysiology ... Presentation • Management ... #Prophylaxis #criticalcare ... #pharmacology # ... management
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Vaughan Williams Classification ... force (negative inotropy ... #Classification ... #Classes #pathophysiology
Delirium in the ICU

Defining delirium
Types of delirium
Consequences of delirium
Reversible causes of delirium
Drug-induced delirium
Non-pharmacologic management of delirium
Pharmacologic
delirium Reversible causes ... management of delirium ... Pharmacologic ... management of delirium ... #management #criticalcare