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diagnosis rheumatology table vasculitis allergy hypersensitivity ana antinuclear arthritis compared cryoglobulinemia cryoglobulins dermatology druginduced erythemas management pathophysiology patterns rheumatic testing
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: Systemic lupus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... : Lupus (SLE), Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... rash • Erythematous ... lupus erythematosus ... #Systemic #Lupus
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Action: IgG/lgM antibodies ... , Haemolytic disease ... lupus erythematosus ... #table #classification ... #comparison
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... during hemolytic disease ... lupus erythematosus ... - Contact dermatitis ... #Classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months to years) Systemic ... Lupus Erythematosus ... Evolution: Chronic disease ... #sle #comparison
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... lupus erythematosus ... (SLE), rheumatoid ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... rheumatic diseases ... lupus erythematosus ... , drug reactions ... #classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... Tests for All Types ... ANA and RF (if clinical ... #Disease #Rheumatoid
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
Erythema ab igne • A dermatosis ... form of delayed-type ... presenting with erythematous ... observed in acute rheumatic ... #table #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
rheumatic diseases ... , such as SLE, atherosclerotic ... disease, drug reactions ... ischemia • Skin: Erythematous ... , mucositis • Rash
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