7 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... lupus erythematosus ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... Lupus Erythematosus ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Pigmented Purpuric Dermatosis ... Vasculitis: • Hypersensitivity ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... reaction, Haemolytic disease ... glomerulonephritis, Systemic ... lupus erythematosus ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... against MPO • Complement ... Serologies for Cryoglobulins ... #diagnosis #rheumatology ... #classification
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Erythema ab igne • A dermatosis ... of delayed-type hypersensitivity ... presenting with erythematous ... #differential # ... diagnosis #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
ischemia • Skin: Erythematous ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... inflammation Hypersensitivity ... #Diagnosis #Rheumatology