9 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... cytoplasmic antibody ... lupus erythematosus ... #classification ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... Lupus Erythematosus ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Pigmented Purpuric Dermatosis ... /HSP • Cryoglobulinemia ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... lupus erythematosus ... , and SLE) • Urinalysis ... #rheumatology # ... classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... reaction, Haemolytic disease ... lupus erythematosus ... #classification ... #comparison
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... alopecia Differential ... • Type-I Interferonopathies ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... as SLE, atherosclerotic ... often causes arthritis ... + MPO) Cryoglobulinemic ... #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Divided Into Two Types ... malignancies, vasculitis ... processes: • Systemic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Erythema ab igne • A dermatosis ... form of delayed-type ... of necrotizing vasculitis ... #table #differential ... #diagnosis #dermatology